General Information

    • DRAMP ID

    • DRAMP04668

    • Peptide Name

    • Coprisin

    • Source

    • Copris tripartitus

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • VTCDVLSFEAKGIAVNHSACALHCIALRKKGGSCQNGVCVCRN

    • Sequence Length

    • 43

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04668 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP04668.

Physicochemical Information

    • Formula

    • C186H312N60O56S6

    • Absent Amino Acids

    • MPWY

    • Common Amino Acids

    • C

    • Mass

    • 4477.25

    • PI

    • 8.67

    • Basic Residues

    • 7

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 16

    • Net Charge

    • +5

    • Boman Index

    • -41.3

    • Hydrophobicity

    • 0.358

    • Aliphatic Index

    • 90.7

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 375

    • Absorbance 280nm

    • 8.93

    • Polar Residues

    • 17

DRAMP04668

DRAMP04668 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure?activity relationships.

    • Reference

    • Biochim Biophys Acta. 2013 Feb;1828(2):271-283.

    • Author

    • Lee E, Kim JK, Shin S, Jeong KW, Shin A, Lee J, Lee DG, Hwang JS, Kim Y.