General Information

    • DRAMP ID

    • DRAMP04681

    • Peptide Name

    • Antiviral serine protease

    • Source

    • Eisenia foetida (Common brandling worm) (Common dung-worm)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • VIAGGXAAIIG

    • Sequence Length

    • 11

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04681 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04681.

Physicochemical Information

    • Formula

    • C38H66N10O10

    • Absent Amino Acids

    • CDEFHKLMNPQRSTWY

    • Common Amino Acids

    • AGI

    • Mass

    • 952.35

    • PI

    • 5.49

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 7

    • Net Charge

    • 0

    • Boman Index

    • 2705

    • Hydrophobicity

    • 1.991

    • Aliphatic Index

    • 160

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP04681

Comments Information

    • Function

    • Serine protease which has antiviral activity against cucumber mosaic virus and tobacco mosaic virus.

Literature Information

  • ·Literature 1

    • Title

    • A novel anti-plant viral protein from coelomic fluid of the earthworm Eisenia foetida: purification, characterization and its identification as a serine protease.

    • Reference

    • Comp Biochem Physiol B Biochem Mol Biol. 2008 Dec;151(4):381-385.

    • Author

    • Ueda M, Noda K, Nakazawa M, Miyatake K, Ohki S, Sakaguchi M, Inouye K.