General Information

    • DRAMP ID

    • DRAMP04683

    • Peptide Name

    • NADPH oxidoreductase

    • Source

    • Bombyx mori (Silk moth)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • SMIGGVMSKG

    • Sequence Length

    • 10

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antiviral

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04683 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04683.

Physicochemical Information

    • Formula

    • C39H71N11O13S2

    • Absent Amino Acids

    • ACDEFHLNPQRTWY

    • Common Amino Acids

    • G

    • Mass

    • 966.18

    • PI

    • 8.47

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +1

    • Boman Index

    • 413

    • Hydrophobicity

    • 0.58

    • Aliphatic Index

    • 68

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP04683

Comments Information

    • Function

    • NADPH oxidoreductase. Has antiviral activity against BmNPV.

    • Miscellaneous

    • Expressed at high levels in BmNPV-resistant strains. Expressed at lower levels in moderately resistant and susceptible strains.

Literature Information

  • ·Literature 1

    • Title

    • Identification of a soluble NADPH oxidoreductase (BmNOX) with antiviral activities in the gut juice of Bombyx mori.

    • Reference

    • Biosci Biotechnol Biochem. 2007 Jan;71(1):200-205.

    • Author

    • Selot R, Kumar V, Shukla S, Chandrakuntal K, Brahmaraju M, Dandin SB, Laloraya M, Kumar PG.