General Information

    • DRAMP ID

    • DRAMP04684

    • Peptide Name

    • Bacteriocin BAC-IB17

    • Source

    • Bacillus subtilis

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • NKPEALVDYTGVXNS

    • Sequence Length

    • 15

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

      • Gram-positive bacteria: M. luteus, methicillin-resistant S. aureus, methicillin-sensitive S. aureus and B. stearothermophilus;
      • Gram- negative bacteria: E. coli, S. typhi.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP04684 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP04684.

Physicochemical Information

    • Formula

    • C65H101N17O23

    • Absent Amino Acids

    • CFHIMQRW

    • Common Amino Acids

    • NV

    • Mass

    • 1617.96

    • PI

    • 4.37

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 4

    • Net Charge

    • -1

    • Boman Index

    • -2472

    • Hydrophobicity

    • -0.58

    • Aliphatic Index

    • 71.33

    • Half Life

      • Mammalian:1.4 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 106.43

    • Polar Residues

    • 6

DRAMP04684

Comments Information

    • Function

    • Has bactericidal activity.

    • Miscellaneous

    • On the 2D-gel the determined pI of this protein is

Literature Information

  • ·Literature 1

    • Title

    • Isolation, purification and characterization of bacteriocin (BAC-IB17) produced from Bacillus subtilis KIBGE-IB17.

    • Reference

    • Submitted (AUG-2013) to UniProtKB

    • Author

    • Ansari A, Siddiqui NN, Zohra RR, Aman A, Qader SA.