• DRAMP ID

    • DRAMP04702
    • Peptide Name

    • 38 kDa autolysin (Beta-glycosidase; Peptidoglycan hydrolase)
    • Source

    • Mycobacterium phlei
    • Family

    • Not found
    • Gene

    • lytA
    • Sequence

    • VAVKATTTEEETEIPAK
    • Sequence Length

    • 17
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Toxin
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP04702 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP04702.
    • Formula

    • C78H133N19O30
    • Absent Amino Acids

    • CDFGHLMNQRSWY
    • Common Amino Acids

    • ET
    • Mass

    • 1817.02
    • PI

    • 4.49
    • Basic Residues

    • 2
    • Acidic Residues

    • 4
    • Hydrophobic Residues

    • 6
    • Net Charge

    • -2
    • Boman Index

    • -3019
    • Hydrophobicity

    • -0.465
    • Aliphatic Index

    • 74.71
    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP04702

    • Function

    • Hydrolyzes the cell walls of mycobacteria. May play an important role in cell wall growth and cell separation.
    • Biophysicochemical properties

    • pH dependence (Optimum pH is 7.5).
    • PTM

    • The N-terminus is blocked (Probable).
  • ·Literature 1
    • Title

    • Partial characterization of a major autolysin from Mycobacterium phlei.
    • Reference

    • Microbiology. 1999 Jan;145 ( Pt 1):169-176.
    • Author

    • Li ZS, Beveridge TJ, Betts J, Clarke AJ.