General Information
-
DRAMP ID
- DRAMP18097
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Peptide Name
- Kunitz-type serine protease inhibitor U1-aranetoxin-Av1a (U1-AATX-Av1a; Toxin 1; AvTox-1)
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Source
- Araneus ventricosus (Orbweaver spider) (Epeira ventricosa)
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Family
- Belongs to the venom Kunitz-type family
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Gene
- Not found
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Sequence
- MPFHYFPKLNPITWIPGWIPGLGKDRCLLPKVTGPCKASLTRYYYDKDTKACVEFIYGGCRGNRNNFKRKDECEKACTDH
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Sequence Length
- 80
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UniProt Entry
- Q8T3S7
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Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Insecticidal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18097.
Physicochemical Information
-
Formula
- C418H636N114O112S7
Absent Amino Acids
- Q
Common Amino Acids
- K
Mass
- 9274.76
PI
- 9.11
Basic Residues
- 16
Acidic Residues
- 8
Hydrophobic Residues
- 20
Net Charge
- +8
-
Boman Index
- -10000
Hydrophobicity
- -0.671
Aliphatic Index
- 54.88
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 18825
Absorbance 280nm
- 238.29
Polar Residues
- 28
DRAMP18097
Comments Information
Function
- Putative insecticidal toxin that may inhibit trypsin.##Miscellaneous
Literature Information
- ·Literature 1
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Title
- Molecular cloning of two cDNAs encoding an insecticidal toxin fromthe spider, Araneus ventricosus, and construction of a recombinantbaculovirus expressing a spider toxin.
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Pubmed ID
- PubMed ID is not available
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Reference
- Int. J. Ind. Entomol. 4:43-49 (2002)
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Author
- Jung E.H., Lee K.S. , Han J.H., Je Y.H., Chang J.H., Roh J.Y., Sohn H.D., Jin B.R.