General Information

    • DRAMP ID

    • DRAMP18135

    • Peptide Name

    • Peptide Hp1478 (Non-disulfide-bridged peptide 5; NDBP-5)

    • Source

    • Heterometrus petersii (Asian forest scorpion)

    • Family

    • Belongs to the scorpion NDBP 5 family

    • Gene

    • Not found

    • Sequence

    • ILGKFCDEIKRIV

    • Sequence Length

    • 13

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18135 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18135.

Physicochemical Information

    • Formula

    • C70H120N18O18S

    • Absent Amino Acids

    • AHMNPQSTWY

    • Common Amino Acids

    • I

    • Mass

    • 1533.89

    • PI

    • 8.2

    • Basic Residues

    • 3

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +1

    • Boman Index

    • -1263

    • Hydrophobicity

    • 0.546

    • Aliphatic Index

    • 142.31

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 2

DRAMP18135

Comments Information

    • Function

    • Amphipathic peptide with antimicrobial activity (By similarity). Does not show antiviral activity.

Literature Information

  • ·Literature 1

    • Title

    • Inhibitory activity and mechanism of two scorpion venom peptidesagainst herpes simplex virus type 1.

    • Reference

    • Antiviral ReS. 102:1-10 (2014).

    • Author

    • Hong W., Li T., Song Y., Zhang R., Zeng Z., Han S. , Zhang X., Wu Y., Li W., Cao Z.