General Information
-
DRAMP ID
- DRAMP18138
-
Peptide Name
- Peptide Hp1165 (Non-disulfide-bridged peptide 5; NDBP-5)
-
Source
- Heterometrus petersii (Asian forest scorpion)
-
Family
- Belongs to the scorpion NDBP 5 family
-
Gene
- Not found
-
Sequence
- ILGEIWKGIKDIL
-
Sequence Length
- 13
-
UniProt Entry
- P0DME7
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18138.
Physicochemical Information
-
Formula
- C348H559N83O102S3
Absent Amino Acids
- CHPY
Common Amino Acids
- L
Mass
- 1497.84
PI
- 6.07
Basic Residues
- 7
Acidic Residues
- 12
Hydrophobic Residues
- 30
Net Charge
- -5
-
Boman Index
- -5974
Hydrophobicity
- 0.282
Aliphatic Index
- 125.22
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5500
Absorbance 280nm
- 83.33
Polar Residues
- 12
DRAMP18138
Comments Information
Function
- Amphipathic peptide with antimicrobial activity (By similarity). Does not show antiviral activity.
Literature Information
- ·Literature 1
-
Title
- Molecular diversity of toxic components from the scorpionHeterometrus petersii venom revealed by proteomic and transcriptomeanalysiS.
-
Pubmed ID
- 20443192
-
Reference
- Proteomics 10:2471-2485 (2010).
-
Author
- Ma Y., Zhao Y., Zhao R., Zhang W., He Y., Wu Y., Cao Z., Guo L., Li W.
- ·Literature 2
-
Title
- Inhibitory activity and mechanism of two scorpion venom peptidesagainst herpes simplex virus type 1.
-
Pubmed ID
- 24315793
-
Reference
- Antiviral ReS. 102:1-10 (2014).
-
Author
- Hong W., Li T., Song Y., Zhang R., Zeng Z., Han S. , Zhang X., Wu Y., Li W., Cao Z.