General Information
-
DRAMP ID
- DRAMP18143
-
Peptide Name
- Toxin OAIP 5
-
Source
- Selenotypus plumipes (Australian featherleg tarantula)
-
Family
- Belongs to the huwentoxin-2 family
-
Gene
- Not found
-
Sequence
- EELEAKDVIESKALATLDEER
-
Sequence Length
- 21
-
UniProt Entry
- P0DM69
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Insecticidal
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18143.
Physicochemical Information
-
Formula
- C384H631N103O111S8
Absent Amino Acids
- P
Common Amino Acids
- LK
Mass
- 2388.61
PI
- 4.17
Basic Residues
- 13
Acidic Residues
- 11
Hydrophobic Residues
- 31
Net Charge
- +2
-
Boman Index
- -8403
Hydrophobicity
- 0.108
Aliphatic Index
- 105.13
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 8855
Absorbance 280nm
- 115
Polar Residues
- 21
DRAMP18143
Comments Information
Function
- Probable ion channel inhibitor. Shows insecticidal activity when injected into mealwormS.
Literature Information
- ·Literature 1
-
Title
- SVM-based prediction of propeptide cleavage sites in spider toxinsidentifies toxin innovation in an australian tarantula.
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Pubmed ID
- 23894279
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Reference
- PLoS ONE 8:E66279-E66279 (2013)
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Author
- Wong E.S. , Hardy M. C. , Wood D., Bailey T., King G.F.