General Information

    • DRAMP ID

    • DRAMP18216

    • Peptide Name

    • Cerein 7A(Bacteriocin)

    • Source

    • Bacillus cereus Bc7

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • Not found

    • Sequence

    • GWGDVLCVAGTIGGAGTGGLGGAAAGSAVPVIGTGIGGAIGGVSGGLTGAATFC

    • Sequence Length

    • 54

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

    • Gram-positive (wide range)

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18216 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18216.

Physicochemical Information

    • Formula

    • C195H315N55O64S2

    • Absent Amino Acids

    • EHKMNQRY

    • Common Amino Acids

    • G

    • Mass

    • 4518.1

    • PI

    • 3.8

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 23

    • Net Charge

    • -1

    • Boman Index

    • 6923

    • Hydrophobicity

    • 1.024

    • Aliphatic Index

    • 94.07

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5625

    • Absorbance 280nm

    • 106.13

    • Polar Residues

    • 29

DRAMP18216

DRAMP18216 chydropathy plot

Comments Information

    • When the purified cerein 7A and 7B were combined at a 1

    • 1 ratio, no synergistic activity was observed between the two bacteriocins.

Literature Information

  • ·Literature 1

    • Title

    • Purification and sequencing of cerein 7B, a novel bacteriocin produced by Bacillus cereus Bc7.

    • Reference

    • FEMS Microbiol Lett.

    • Author

    • Osc
  • ·Literature 2

    • Title

    • Characterization and mechanism of action of cerein 7, a bacteriocin produced by Bacillus cereus Bc7.

    • Reference

    • J Appl Microbiol.

    • Author