General Information

    • DRAMP ID

    • DRAMP18217

    • Peptide Name

    • Licheniocin 50.2(Bacteriocin)

    • Source

    • Bacillus licheniformis VPS50.2

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • Not found

    • Sequence

    • WEEYNIIXQLGNKGQ

    • Sequence Length

    • 15

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

    • Gram-positive

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18217 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C76H112N20O23

    • Absent Amino Acids

    • ACDFHMPRSTV

    • Common Amino Acids

    • EGINQ

    • Mass

    • 1803.19

    • PI

    • 4.53

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 4

    • Net Charge

    • -1

    • Boman Index

    • -2470

    • Hydrophobicity

    • -1.007

    • Aliphatic Index

    • 78

    • Half Life

      • Mammalian:2.8 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 6990

    • Absorbance 280nm

    • 499.29

    • Polar Residues

    • 5

DRAMP18217

Comments Information

    • Fuction

    • The bacteriocin activity was insensitive to lysozyme and proteinase K, heat stable after incubation at 100 Celsius degree for 30 min and over wide range of pH (2

Literature Information

  • ·Literature 1

    • Title

    • Treatment of chronic recurring parotitis with the protease inhibitor aprotinin (trasylol).

    • Reference

    • Laryngol Rhinol Otol (Stuttg).

    • Author

    • Maier H, Adler D.