General Information
-
DRAMP ID
- DRAMP18224
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Peptide Name
- Ala-6-fenycin (Bacteriocin)
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Source
- Bacillus sp. strain P34
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Family
- Belongs to the lipopeptides family
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Gene
- Not found
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Sequence
- EKYTEAPEYI
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Sequence Length
- 10
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UniProt Entry
- No entry found
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Protein Existence
Activity Information
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Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Antiviral
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Target Organism
- Gram-positive
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
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Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- An acyl chain (C15 to C17 carbons) is attached to E1, residue 2 is an ornithine (represented as K), and the carboxylic group of C-terminal I10 forms an ester bond with the side chain of Y3.
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Helical Wheel Diagram
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PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18224.
Physicochemical Information
-
Formula
- C57H83N11O20
Absent Amino Acids
- CDFGHLMNQRSVW
Common Amino Acids
- E
Mass
- 1242.35
PI
- 4.25
Basic Residues
- 1
Acidic Residues
- 3
Hydrophobic Residues
- 2
Net Charge
- -2
-
Boman Index
- -2210
Hydrophobicity
- -1.3
Aliphatic Index
- 49
Half Life
-
- Mammalian:1 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 2980
Absorbance 280nm
- 331.11
Polar Residues
- 3
DRAMP18224
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Antiviral activity of a Bacillus sp. P34 peptide against pathogenic viruses of domestic animals.
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Pubmed ID
- 25477947
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Reference
- Braz J Microbiol. 2014 Oct 9;45(3):1089-94. eCollection 2014.
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Author
- Scopel e Silva D, de Castro CC, da Silva e Silva F, Sant'anna V, Vargas GD, de Lima M, Fischer G, Brandelli A, da Motta Ade S, H