General Information

    • DRAMP ID

    • DRAMP18224

    • Peptide Name

    • Ala-6-fenycin (Bacteriocin)

    • Source

    • Bacillus sp. strain P34

    • Family

    • Belongs to the lipopeptides family

    • Gene

    • Not found

    • Sequence

    • EKYTEAPEYI

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Antiviral

    • Target Organism

    • Gram-positive

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • An acyl chain (C15 to C17 carbons) is attached to E1, residue 2 is an ornithine (represented as K), and the carboxylic group of C-terminal I10 forms an ester bond with the side chain of Y3.

    • Helical Wheel Diagram

    • DRAMP18224 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18224.

Physicochemical Information

    • Formula

    • C57H83N11O20

    • Absent Amino Acids

    • CDFGHLMNQRSVW

    • Common Amino Acids

    • E

    • Mass

    • 1242.35

    • PI

    • 4.25

    • Basic Residues

    • 1

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 2

    • Net Charge

    • -2

    • Boman Index

    • -2210

    • Hydrophobicity

    • -1.3

    • Aliphatic Index

    • 49

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 331.11

    • Polar Residues

    • 3

DRAMP18224

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antiviral activity of a Bacillus sp. P34 peptide against pathogenic viruses of domestic animals.

    • Reference

    • Braz J Microbiol. 2014 Oct 9;45(3):1089-94. eCollection 2014.

    • Author

    • Scopel e Silva D, de Castro CC, da Silva e Silva F, Sant'anna V, Vargas GD, de Lima M, Fischer G, Brandelli A, da Motta Ade S, H