• DRAMP ID

    • DRAMP18228
    • Peptide Name

    • Gageostatin C (Bacteriocin)
    • Source

    • Bacillus subtilis
    • Family

    • Belongs to the lipopeptides family
    • Gene

    • Not found
    • Sequence

    • LLDVLLE
    • Sequence Length

    • 7
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
    • Target Organism

    • Gram-positive, Gram-negative
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Leu-Leu-Asp-Val-Leu-Leu-Glu-(E)-7,9-dimethylundec-2-enoic acid
    • Helical Wheel Diagram

    • DRAMP18228 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18228.
    • Formula

    • C38H67N7O12
    • Absent Amino Acids

    • ACFGHIKMNPQRSTWY
    • Common Amino Acids

    • L
    • Mass

    • 813.99
    • PI

    • 3.67
    • Basic Residues

    • 0
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 5
    • Net Charge

    • -2
    • Boman Index

    • 819
    • Hydrophobicity

    • 1.771
    • Aliphatic Index

    • 264.29
    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 0

DRAMP18228

    • surfactin like heptapeptides, cytotoxic. It is noteworthy that these compounds 1

  • ·Literature 1
    • Title

    • Gageostatins A-C, antimicrobial linear lipopeptides from a marine Bacillus subtilis.
    • Reference

    • Mar Drugs. 2014 Jan 31;12(2):871-85.
    • Author

    • Tareq FS, Lee MA, Lee HS, Lee JS, Lee YJ, Shin HJ.