General Information

    • DRAMP ID

    • DRAMP18230

    • Peptide Name

    • Gageotetrin B (Bacteriocin)

    • Source

    • Bacillus subtilis

    • Family

    • Belongs to the lipopeptides family

    • Gene

    • Not found

    • Sequence

    • LLLE

    • Sequence Length

    • 4

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

    • Gram-positive, Gram-negative

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Leu-Leu-Leu-OMeGlu-3-hydroxy-11-methyltridecanoic acid (HTDA)

    • Helical Wheel Diagram

    • DRAMP18230 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18230.

Physicochemical Information

    • Formula

    • C23H42N4O7

    • Absent Amino Acids

    • ACDFGHIKMNPQRSTVW

    • Common Amino Acids

    • L

    • Mass

    • 486.61

    • PI

    • 4

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 3

    • Net Charge

    • -1

    • Boman Index

    • 795

    • Hydrophobicity

    • 1.975

    • Aliphatic Index

    • 292.5

    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 0

DRAMP18230

Comments Information

    • Noncytotoxic Antimicrobial Linear Lipopeptides

Literature Information

  • ·Literature 1

    • Title

    • Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.

    • Reference

    • Org Lett. 2014 Feb 7;16(3):928-31.

    • Author

    • Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ.