General Information
-
DRAMP ID
- DRAMP18231
-
Peptide Name
- Gageotetrin C (Bacteriocin)
-
Source
- Bacillus subtilis
-
Family
- Belongs to the lipopeptides family
-
Gene
- Not found
-
Sequence
- LLLE
-
Sequence Length
- 4
-
UniProt Entry
- No entry found
-
Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal, Antibacterial, Anti-Gram+, Anti-Gram-
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Target Organism
- Gram-positive, Gram-negative
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Leu-Leu-Leu-Glu-3-hydroxy-8,10-dimethyldodecanoic acid (HDDA)
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18231.
Physicochemical Information
-
Formula
- C23H42N4O7
Absent Amino Acids
- ACDFGHIKMNPQRSTVW
Common Amino Acids
- L
Mass
- 486.61
PI
- 4
Basic Residues
- 0
Acidic Residues
- 1
Hydrophobic Residues
- 3
Net Charge
- -1
-
Boman Index
- 795
Hydrophobicity
- 1.975
Aliphatic Index
- 292.5
Half Life
-
- Mammalian:5.5 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 0
DRAMP18231
Comments Information
Noncytotoxic Antimicrobial Linear Lipopeptides
Literature Information
- ·Literature 1
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Title
- Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.
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Pubmed ID
- 24502521
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Reference
- Org Lett. 2014 Feb 7;16(3):928-31.
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Author
- Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ.