• DRAMP ID

    • DRAMP18237
    • Peptide Name

    • Fengycin A(Bacteriocin)
    • Source

    • Bacillus subtilis K1
    • Family

    • Belongs to the lipopeptides family
    • Gene

    • Not found
    • Sequence

    • EKYTEAPEYI
    • Sequence Length

    • 10
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
    • Target Organism

    • Gram-positive, Gram-negative
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • K2 is Orn. The structure consists of a cyclic peptide lactone formed between the phenolic -OH of Tyr3 and the C-terminal -COOH of an amino acid at position 10. The N-terminus of the decapeptide segment is acylated with a beta-hydroxy fatty acid (beta-OH FA).
    • Helical Wheel Diagram

    • DRAMP18237 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18237.
    • Formula

    • C57H83N11O20
    • Absent Amino Acids

    • CDFGHLMNQRSVW
    • Common Amino Acids

    • E
    • Mass

    • 1242.35
    • PI

    • 4.25
    • Basic Residues

    • 1
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 2
    • Net Charge

    • -2
    • Boman Index

    • -2210
    • Hydrophobicity

    • -1.3
    • Aliphatic Index

    • 49
    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 2980
    • Absorbance 280nm

    • 331.11
    • Polar Residues

    • 3

DRAMP18237

    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins.
    • Reference

    • J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.
    • Author

    • Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P.