General Information

    • DRAMP ID

    • DRAMP18237

    • Peptide Name

    • Fengycin A(Bacteriocin)

    • Source

    • Bacillus subtilis K1

    • Family

    • Belongs to the lipopeptides family

    • Gene

    • Not found

    • Sequence

    • EKYTEAPEYI

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-

    • Target Organism

    • Gram-positive, Gram-negative

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • K2 is Orn. The structure consists of a cyclic peptide lactone formed between the phenolic -OH of Tyr3 and the C-terminal -COOH of an amino acid at position 10. The N-terminus of the decapeptide segment is acylated with a beta-hydroxy fatty acid (beta-OH FA).

    • Helical Wheel Diagram

    • DRAMP18237 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18237.

Physicochemical Information

    • Formula

    • C57H83N11O20

    • Absent Amino Acids

    • CDFGHLMNQRSVW

    • Common Amino Acids

    • E

    • Mass

    • 1242.35

    • PI

    • 4.25

    • Basic Residues

    • 1

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 2

    • Net Charge

    • -2

    • Boman Index

    • -2210

    • Hydrophobicity

    • -1.3

    • Aliphatic Index

    • 49

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 331.11

    • Polar Residues

    • 3

DRAMP18237

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins.

    • Reference

    • J Am Soc Mass Spectrom. 2012 Oct;23(10):1716-28. Epub 2012 Jul 31.

    • Author

    • Pathak KV, Keharia H, Gupta K, Thakur SS, Balaram P.