• DRAMP ID

    • DRAMP18264
    • Peptide Name

    • Enterocin W beta(Bacteriocin)
    • Source

    • Enterococcus faecalis NKR-4-1
    • Family

    • Belongs to the lantibiotics family (Class I bacteriocin)
    • Gene

    • Not found
    • Sequence

    • VTTSIPCTVMVSAAVCPTLVCSNKCGGRG
    • Sequence Length

    • 29
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

    • Gram-positive (Narrow)
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Cell membrane
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Enterocin Wbeta was proven to have 3 dehydrated amino acids as well as 2 and 2 Lan and MeLan residues, respectively. The amino acid sequences of the prepeptides of enterocin W showed the highest identity with those of plantaricins Walpha and Wbeta (63.3 and 44.7%, respectively).
    • Helical Wheel Diagram

    • DRAMP18264 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18264.
    • Formula

    • C117H204N34O38S5
    • Absent Amino Acids

    • DEFHQWY
    • Common Amino Acids

    • V
    • Mass

    • 2855.41
    • PI

    • 8.54
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Net Charge

    • +2
    • Boman Index

    • -364
    • Hydrophobicity

    • 0.803
    • Aliphatic Index

    • 83.79
    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 250
    • Absorbance 280nm

    • 8.93
    • Polar Residues

    • 15

DRAMP18264

DRAMP18264 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Isolation and characterization of enterocin W, a novel two-peptide lantibiotic produced by Enterococcus faecalis NKR-4-1.
    • Reference

    • Appl Environ Microbiol. 2012 Feb;78(3):900-3.
    • Author

    • Sawa N, Wilaipun P, Kinoshita S, Zendo T, Leelawatcharamas V, Nakayama J, Sonomoto K.