General Information
-
DRAMP ID
- DRAMP18268
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Peptide Name
- Enterocin NKR-5-3C(Bacteriocin)
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Source
- Enterococcus faecium NKR-5-3
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Family
- Belongs to the class IIa bacteriocin
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Gene
- enkC
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Sequence
- ATYYGNGLYCNSKKCWVEWGITGGCLAQYAIGGWLGGAVPGKC
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Sequence Length
- 43
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UniProt Entry
- I7H7S7
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Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
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Target Organism
- Gram-positive
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Ent53C is a novel class IIa bacteriocin that contains a YGNVL motif sequence and two disul?de bridges.
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18268.
Physicochemical Information
-
Formula
- C205H300N52O56S4
Absent Amino Acids
- DFHMR
Common Amino Acids
- G
Mass
- 4517.19
PI
- 8.47
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 14
Net Charge
- +2
-
Boman Index
- 1005
Hydrophobicity
- 0.107
Aliphatic Index
- 68.14
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 22710
Absorbance 280nm
- 540.71
Polar Residues
- 23
DRAMP18268
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Gene cluster responsible for secretion of and immunity to multiple bacteriocins, the NKR-5-3 enterocins.
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Pubmed ID
- 25149515
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Reference
- Appl Environ Microbiol. 2014 Nov;80(21):6647-55.
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Author
- Ishibashi N, Himeno K, Masuda Y, Perez RH, Iwatani S, Zendo T, Wilaipun P, Leelawatcharamas V, Nakayama J, Sonomoto K.