General Information

    • DRAMP ID

    • DRAMP18282

    • Peptide Name

    • Plantaricin ZJ008 (Bacteriocin)

    • Source

    • Lactobacillus plantarum ZJ008

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • QWGGG

    • Sequence Length

    • 5

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • broad-spectrum

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrane

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • The sequence showed no homology with known bacteriocins.

    • Helical Wheel Diagram

    • DRAMP18282 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

Physicochemical Information

    • Formula

    • C22H29N7O7

    • Absent Amino Acids

    • ACDEFHIKLMNPRSTVY

    • Common Amino Acids

    • G

    • Mass

    • 503.51

    • PI

    • 5.52

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 1

    • Net Charge

    • 0

    • Boman Index

    • -39

    • Hydrophobicity

    • -1.12

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 1375

    • Polar Residues

    • 3

DRAMP18282

Comments Information

    • Warning

    • only the N-terminal amino acid sequence has been elucidated for this 20-residue bacteriocin. This bacteriocin was highly thermostable (121 Celsius degree, 30 min) and exhibited narrow pH stability (pH 4.0

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterisation of plantaricin ZJ008, a novel bacteriocin against Staphylococcus spp. from Lactobacillus plantarum ZJ008.

    • Reference

    • Food Chem. 2014 Dec 15;165:216-23.

    • Author

    • Zhu X, Zhao Y, Sun Y, Gu Q.