General Information

    • DRAMP ID

    • DRAMP18283

    • Peptide Name

    • Plantaricin ZJ5 (Bacteriocin)

    • Source

    • Lactobacillus plantarum ZJ5

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • Not found

    • Sequence

    • KTKQQFLIKAQTQLFKVFGYTL

    • Sequence Length

    • 22

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • broad-spectrum

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18283 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18283.

Physicochemical Information

    • Formula

    • C126H200N30O31

    • Absent Amino Acids

    • CDEHMNPRSW

    • Common Amino Acids

    • KQ

    • Mass

    • 2631.16

    • PI

    • 10.18

    • Basic Residues

    • 4

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +4

    • Boman Index

    • -1680

    • Hydrophobicity

    • -0.141

    • Aliphatic Index

    • 88.64

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 70.95

    • Polar Residues

    • 5

DRAMP18283

DRAMP18283 chydropathy plot

Comments Information

    • Comment

    • 37% similar to Warnericin RK.The peptide activity was lost by treatment with pepsin and proteinase K (62%) but not affected by lipase or alpha-amylase.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of Plantaricin ZJ5, a new bacteriocin produced by Lactobacillus plantarum ZJ5.

    • Reference

    • PLoS One. 2014 Aug 22;9(8):e105549.

    • Author

    • Song DF, Zhu MY, Gu Q.