General Information

    • DRAMP ID

    • DRAMP18289

    • Peptide Name

    • Bactofencin A (Bacteriocin)

    • Source

    • Lactobacillus salivarius DPC6502

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • Not found

    • Sequence

    • KRKKHRCRVYNNGMPTGMYRWC

    • Sequence Length

    • 22

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

    • Gram-positive

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18289 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18289.

Physicochemical Information

    • Formula

    • C119H190N42O28S4

    • Absent Amino Acids

    • ADEFILQS

    • Common Amino Acids

    • R

    • Mass

    • 2785.32

    • PI

    • 10.56

    • Basic Residues

    • 8

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +8

    • Boman Index

    • -8161

    • Hydrophobicity

    • -1.523

    • Aliphatic Index

    • 13.18

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 8605

    • Absorbance 280nm

    • 409.76

    • Polar Residues

    • 9

DRAMP18289

DRAMP18289 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Bactofencin A, a new type of cationic bacteriocin with unusual immunity.

    • Reference

    • MBio. 2013 Oct 29;4(6):e00498-13.

    • Author

    • O'Shea EF, O'Connor PM, O'Sullivan O, Cotter PD, Ross RP, Hill C.