General Information

    • DRAMP ID

    • DRAMP18293

    • Peptide Name

    • Bacteriocin J46 (Bacteriocin)

    • Source

    • Lactococcus lactis J46

    • Family

    • Belongs to the lantibiotics family (Class I bacteriocin)

    • Gene

    • lcp J

    • Sequence

    • KGGSGVIHTISHEVIYNSWNFVFTCCS

    • Sequence Length

    • 27

    • Protein Existence

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18293 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18293.

Physicochemical Information

    • Formula

    • C134H197N35O39S2

    • Absent Amino Acids

    • ADLMPQR

    • Common Amino Acids

    • S

    • Mass

    • 2986.37

    • PI

    • 6.9

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +2

    • Boman Index

    • -1329

    • Hydrophobicity

    • 0.293

    • Aliphatic Index

    • 75.56

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 7115

    • Absorbance 280nm

    • 273.65

    • Polar Residues

    • 14

DRAMP18293

DRAMP18293 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Comparative effectiveness of nisin and bacteriocin J46 at different pH values.

    • Reference

    • Lett Appl Microbiol. 1996 Jan;22(1):76-9.

    • Author

    • Huot E, Barrena-Gonzalez C, Petitdemange H.