General Information

    • DRAMP ID

    • DRAMP18294

    • Peptide Name

    • lactococcin Z(Bacteriocin)

    • Source

    • Lactococcus lactis QU 7

    • Family

    • Belongs to the class IId bacteriocin

    • Gene

    • lczA

    • Sequence

    • ALQFIQNTASGALYYNTKTHKYQYQQTSGA

    • Sequence Length

    • 30

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

    • Target Organism

    • Gram-positive, Gram-negative

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Lactococcin Z showed homology to lactococcins A, B and M.

    • Helical Wheel Diagram

    • DRAMP18294 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18294.

Physicochemical Information

    • Formula

    • C152H227N41O48

    • Absent Amino Acids

    • CDEMPRVW

    • Common Amino Acids

    • Q

    • Mass

    • 3396.72

    • PI

    • 9.31

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +3

    • Boman Index

    • -4752

    • Hydrophobicity

    • -0.793

    • Aliphatic Index

    • 52.33

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5960

    • Absorbance 280nm

    • 205.52

    • Polar Residues

    • 14

DRAMP18294

DRAMP18294 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Identification of Lactococcus-Specific Bacteriocins Produced by Lactococcal Isolates, and the Discovery of a Novel Bacteriocin, Lactococcin Z.

    • Reference

    • Probiotics Antimicrob Proteins. 2015 Sep;7(3):222-31.

    • Author

    • Ishibashi N, Seto H, Koga S, Zendo T, Sonomoto K.