General Information
-
DRAMP ID
- DRAMP18296
-
Peptide Name
- Leucocin H beta(Bacteriocin)
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Source
- Leuconostoc MF215B
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Family
- Belongs to the class IIb bacteriocin
-
Gene
- Not found
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Sequence
- WXAVFXNMAKYMFKSQSKXVVIGFLVAS
-
Sequence Length
- 28
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UniProt Entry
- No entry found
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Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
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Target Organism
- Gram-positive
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- No sequence homology to other known bacteriocins could be demonstrated. It also appeared that the two peptides themselves shared little or no sequence homology.
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18296.
Physicochemical Information
-
Formula
- C136H201N31O29S2
Absent Amino Acids
- CDEHPRT
Common Amino Acids
- V
Mass
- 3186.44
PI
- 10
Basic Residues
- 3
Acidic Residues
- 0
Hydrophobic Residues
- 13
Net Charge
- +3
-
Boman Index
- 917
Hydrophobicity
- 0.679
Aliphatic Index
- 80
Half Life
-
- Mammalian:2.8 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 6990
Absorbance 280nm
- 258.89
Polar Residues
- 6
DRAMP18296
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Characterization, production, and purification of leucocin H, a two-peptide bacteriocin from Leuconostoc MF215B.
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Pubmed ID
- 10387116
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Reference
- Curr Microbiol. 1999 Jul;39(1):43-8.
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Author
- Blom H, Katla T, Holck A, Sletten K, Axelsson L, Holo H.