General Information

    • DRAMP ID

    • DRAMP18297

    • Peptide Name

    • Patellamide D(Bacteriocin)

    • Source

    • Lissoclinum patella

    • Family

    • Belongs to the class I bacteriocin

    • Gene

    • Not found

    • Sequence

    • ISVCITVC

    • Sequence Length

    • 8

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18297 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18297.

Physicochemical Information

    • Formula

    • C35H64N8O11S2

    • Absent Amino Acids

    • ADEFGHKLMNPQRWY

    • Common Amino Acids

    • CIV

    • Mass

    • 837.06

    • PI

    • 5.51

    • Basic Residues

    • 0

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 4

    • Net Charge

    • 0

    • Boman Index

    • 1451

    • Hydrophobicity

    • 2.613

    • Aliphatic Index

    • 170

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 17.86

    • Polar Residues

    • 4

DRAMP18297

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • New cyclic peptides with cytotoxic activity from the ascidian Lissoclinum patella.

    • Reference

    • J Med Chem. 1989 Jun;32(6):1349-54.

    • Author

    • Degnan BM, Hawkins CJ, Lavin MF, McCaffrey EJ, Parry DL, van den Brenk AL, Watters DJ.