General Information

    • DRAMP ID

    • DRAMP18306

    • Peptide Name

    • Pediocin ACCEL(Bacteriocin)

    • Source

    • Pediococcus pentosaceus ACCEL

    • Family

    • Belongs to the class IIa bacteriocin

    • Gene

    • Not found

    • Sequence

    • KYYGNGVTXGKHSXXVDXG

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+

    • Target Organism

    • Gram-positive

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18306 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18306.

Physicochemical Information

    • Formula

    • C69H96N20O19

    • Absent Amino Acids

    • ACEFILMPQRW

    • Common Amino Acids

    • GX

    • Mass

    • 2027.03

    • PI

    • 8.44

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +2

    • Boman Index

    • -2553

    • Hydrophobicity

    • -0.805

    • Aliphatic Index

    • 30.53

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 165.56

    • Polar Residues

    • 9

DRAMP18306

DRAMP18306 chydropathy plot

Comments Information

    • It was inactivated by various proteases and stable at pH 2.0-6.0 and <100 Celsius degree. More than 80% activity was left even after 15 min of heating at 121 Celsius degree and pH 2.0-4.0.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of bacteriocin from Pediococcus pentosaceus ACCEL.

    • Reference

    • J Agric Food Chem. 2004 Mar 10;52(5):1146-51.

    • Author

    • Wu CW, Yin LJ, Jiang ST.