General Information
-
DRAMP ID
- DRAMP18308
-
Peptide Name
- Planosporicin(Bacteriocin)
-
Source
- Planomonospora alba
-
Family
- Belongs to the lantibiotics family (Class I bacteriocin)
-
Gene
- pspA
-
Sequence
- MGISSPALPQNTADLFQLDLEIGVEQSLASPAITSVSWCTPGCTSEGGGSGCSHCC
-
Sequence Length
- 56
-
UniProt Entry
- R4ZCJ5
-
Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- broad-spectrum
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18308.
Physicochemical Information
-
Formula
- C235H371N63O84S6
Absent Amino Acids
- KRY
Common Amino Acids
- S
Mass
- 5615.26
PI
- 3.83
Basic Residues
- 1
Acidic Residues
- 5
Hydrophobic Residues
- 16
Net Charge
- -4
-
Boman Index
- -3135
Hydrophobicity
- 0.188
Aliphatic Index
- 73.21
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5750
Absorbance 280nm
- 104.55
Polar Residues
- 26
DRAMP18308
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- A novel lantibiotic acting on bacterial cell wall synthesis produced by the uncommon actinomycete Planomonospora sp.
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Pubmed ID
- 17469849
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Reference
- Biochemistry. 2007 May 22;46(20):5884-95.
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Author
- Castiglione F, Cavaletti L, Losi D, Lazzarini A, Carrano L, Feroggio M, Ciciliato I, Corti E, Candiani G, Marinelli F, Selva E.