General Information

    • DRAMP ID

    • DRAMP18324

    • Peptide Name

    • Warnericin RK (Bacteriocin)

    • Source

    • Staphylococcus warneri RK

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • MQFITDLIKKAVDFFKGLFGNK

    • Sequence Length

    • 22

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-

    • Target Organism

    • Gram-negative(Narrow)

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Alpha Helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18324 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18324.

Physicochemical Information

    • Formula

    • C122H190N28O30S

    • Absent Amino Acids

    • CEHPRSWY

    • Common Amino Acids

    • FK

    • Mass

    • 2561.08

    • PI

    • 9.52

    • Basic Residues

    • 4

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +2

    • Boman Index

    • -1271

    • Hydrophobicity

    • 0.209

    • Aliphatic Index

    • 88.64

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP18324

DRAMP18324 chydropathy plot

Comments Information

    • Warnericin RK acts as a specific anti-Legionella AMP by permeabilizing the bacterial membrane.

Literature Information

  • ·Literature 1

    • Title

    • Characterization of anti-Legionella activity of warnericin RK and delta-lysin I from Staphylococcus warneri.

    • Reference

    • Peptides. 2008 Jun;29(6):978-84.

    • Author

    • Verdon J, Berjeaud JM, Lacombe C, H
  • ·Literature 2

    • Title

    • Detergent-like activity and alpha-helical structure of warnericin RK, an anti-Legionella peptide.

    • Reference

    • Biophys J. 2009 Oct 7;97(7):1933-40.

    • Author