General Information
-
DRAMP ID
- DRAMP18346
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Peptide Name
- Legonaridin(Bacteriocin)
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Source
- Streptomyces sp. CT34
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Family
- Belongs to the class I bacteriocin
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Gene
- legA
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Sequence
- ITPLATLATPEATPVGFAATSATAAAVNMITHDVTRH
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Sequence Length
- 37
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UniProt Entry
- No entry found
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Protein Existence
Activity Information
-
Biological Activity
- Unknown
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Despite the same chemical features as those observed in cypemycin and grisemycin, legonaridin 1 has a structurally different C-terminus with a free carboxylic acid.
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Helical Wheel Diagram
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PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18346.
Physicochemical Information
-
Formula
- C163H265N45O52S
Absent Amino Acids
- CKQWY
Common Amino Acids
- A
Mass
- 3719.23
PI
- 5.99
Basic Residues
- 3
Acidic Residues
- 2
Hydrophobic Residues
- 17
Net Charge
- +1
-
Boman Index
- -1601
Hydrophobicity
- 0.462
Aliphatic Index
- 90
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 11
DRAMP18346
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate.
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Pubmed ID
- 26256511
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Reference
- Org Biomol Chem. 2015 Oct 7;13(37):9585-92.
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Author
- Rateb ME, Zhai Y, Ehrner E, Rath CM, Wang X, Tabudravu J, Ebel R, Bibb M, Kyeremeh K, Dorrestein PC, Hong K, Jaspars M, Deng H.