General Information
-
DRAMP ID
- DRAMP18348
-
Peptide Name
- RES-701-1(Bacteriocin)
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Source
- Streptomyces spp.
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Family
- Belongs to the class I bacteriocin
-
Gene
- Not found
-
Sequence
- GNWHGTAPDWFFNYYW
-
Sequence Length
- 16
-
UniProt Entry
- No entry found
-
Protein Existence
Activity Information
-
Biological Activity
- Unknown
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18348.
Physicochemical Information
-
Formula
- C103H117N23O24
Absent Amino Acids
- CEIKLMQRSV
Common Amino Acids
- W
Mass
- 2061.2
PI
- 5.08
Basic Residues
- 1
Acidic Residues
- 1
Hydrophobic Residues
- 6
Net Charge
- 0
-
Boman Index
- -1287
Hydrophobicity
- -0.919
Aliphatic Index
- 6.25
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 19480
Absorbance 280nm
- 1298.67
Polar Residues
- 7
DRAMP18348
Comments Information
RES-701-1 is an endothelin B receptor (ET) selective peptidic antagonist.
Literature Information
- ·Literature 1
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Title
- C-terminal modifications of an endothelin antagonist RES-701-1: Production of ETA/ETB dual selective analogs.
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Pubmed ID
- PubMed ID is not available
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Reference
- Letters in Peptide Science. 1997 Jun;4(3):167-170.
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Author
- Shibata K,Yano K,Tanaka T,Matsuda Y,Yamasaki M.