General Information

    • DRAMP ID

    • DRAMP18351

    • Peptide Name

    • Trichamide(Bacteriocin)

    • Source

    • Trichodesmium erythraeum

    • Family

    • Belongs to the class I bacteriocin

    • Gene

    • Not found

    • Sequence

    • EDGLHPRLCSC

    • Sequence Length

    • 11

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Trichamide consists of 11 amino acids, including two cysteine-derived thiazole groups, and is cyclized by an N-C terminal amide bond.

    • Helical Wheel Diagram

    • DRAMP18351 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18351.

Physicochemical Information

    • Formula

    • C49H80N16O17S2

    • Absent Amino Acids

    • AFIKMNQTVWY

    • Common Amino Acids

    • CL

    • Mass

    • 1229.39

    • PI

    • 5.32

    • Basic Residues

    • 2

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 2

    • Net Charge

    • 0

    • Boman Index

    • -2517

    • Hydrophobicity

    • -0.446

    • Aliphatic Index

    • 70.91

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 12.5

    • Polar Residues

    • 4

DRAMP18351

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Structure of trichamide, a cyclic peptide from the bloom-forming cyanobacterium Trichodesmium erythraeum, predicted from the genome sequence.

    • Reference

    • Appl Environ Microbiol. 2006 Jun;72(6):4382-7.

    • Author

    • Sudek S, Haygood MG, Youssef DT, Schmidt EW.