General Information

    • DRAMP ID

    • DRAMP18353

    • Peptide Name

    • Durancin L28-1A (bacteriocin)

    • Source

    • Enterococcus durans L28-1

    • Family

    • Belongs to the class IIa bacteriocin.

    • Gene

    • Not found

    • Sequence

    • ENDHRMPYELNRPNNLSKGGAKCGAAIA

    • Sequence Length

    • 28

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

      • Active against Gram+ bacteria: L. sakei ssp. sakei JCM 1157T, L. sanfranciscensis JCM 5668, L. coryniformis ssp.coryniformis JCM 1164, L. plantarum NRIC 1067, L. animalis JCM 5670, L. pentosus JCM 1558, L. gasseri JCM 5344 , L. helveticus JCM 1554, L. lactis JCM 6123, L. lactis ssp. lactis C101910, L. lactis ssp. lactis IFO 12007 , E. faecium MR006 , E. durans MY411, C. divergens JCM 5816, W. paramesenteroides NRIC 1542, W. kandleri JCM 5817, W. halotolerans JCM 1114, and W. minor JCM 1168T.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18353 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18353.

Physicochemical Information

    • Formula

    • C126H204N42O41S2

    • Absent Amino Acids

    • FQTVW

    • Common Amino Acids

    • AN

    • Mass

    • 3027.38

    • PI

    • 8.28

    • Basic Residues

    • 5

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +2

    • Boman Index

    • -6959

    • Hydrophobicity

    • -0.975

    • Aliphatic Index

    • 56.07

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 55.19

    • Polar Residues

    • 10

DRAMP18353

DRAMP18353 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Durancin L28-1A, a new bacteriocin from Enterococcus durans L28-1, isolated from soil.

    • Reference

    • Lett Appl Microbiol. 2005;40(6):430-5

    • Author

    • Yanagida F, Chen Y, Onda T, Shinohara T.