General Information

    • DRAMP ID

    • DRAMP18361

    • Peptide Name

    • YD1 (bacteriocin)

    • Source

    • Bacillus amyloliquefaciens

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • APKGVQGPNG

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Active against Gram- S. typhimurium KCTC 1925 (MIC 32 ug/ml), E. coli KCTC 1923 (MIC 8 ug/ml), P. aeruginosa KCTC 1637 (MIC 16 ug/ml), Gram+ M. smegmatis ATCC 9341 (MIC 8 ug/ml), S. aureus KCTC 1928, MRSA B15 (MIC 32 ug/ml), E. faecalis ATCC 29212, B. subtilis ATCC 6633, M. luteus ATCC 9341, VRE 2, and VRE5 (MIC 64 ug/ml).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18361 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18361.

Physicochemical Information

    • Formula

    • C39H63N13O12

    • Absent Amino Acids

    • CDEFHILMRSTWY

    • Common Amino Acids

    • G

    • Mass

    • 924.02

    • PI

    • 8.8

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 2

    • Net Charge

    • +1

    • Boman Index

    • -906

    • Hydrophobicity

    • -0.846

    • Aliphatic Index

    • 35.45

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP18361

Comments Information

    • YD1 binds to the plasmid DNA of E. coli.

Literature Information

  • ·Literature 1

    • Title

    • Glycin-rich antimicrobial peptide YD1 from B. amyloliquefaciens, induced morphological alteration in and showed affinity for plasmid DNA of E. coli.

    • Reference

    • AMB Express. 2017 Dec;7(1):8

    • Author

    • Rahman MS, Choi YH, Choi YS, Yoo JC.