General Information
-
DRAMP ID
- DRAMP18427
-
Peptide Name
- MrDN (pellino-1 derived, Crustaceans, arthropods, invertebrates, animals)
-
Source
- Giant freshwater prawn, Macrobrachium rosenbergii
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- DKGRRRSKFVLHRRQCAN
-
Sequence Length
- 18
-
UniProt Entry
- No entry found
-
Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18427.
Physicochemical Information
-
Formula
- C92H159N39O24S
Absent Amino Acids
- EIMPTWY
Common Amino Acids
- R
Mass
- 2227.58
PI
- 11.83
Basic Residues
- 8
Acidic Residues
- 1
Hydrophobic Residues
- 4
Net Charge
- +7
-
Boman Index
- -9869
Hydrophobicity
- -1.672
Aliphatic Index
- 43.33
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 4
DRAMP18427
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Pellino-1 derived cationic antimicrobial prawn peptide: Bactericidal activity, toxicity and mode of action
-
Pubmed ID
- 27648859
-
Reference
- Mol Immunol. 2016 Oct;78:171-182.
-
Author
- Ravichandran G, Kumaresan V, Arasu MV, Al-Dhabi NA, Ganesh MR, Mahesh A, Dhayalan A, Pasupuleti M, Arockiaraj J