General Information

    • DRAMP ID

    • DRAMP18431

    • Peptide Name

    • Armadillidin Q (Gly-rich; Terrestrial Isopod, Crustaceans, arthropods, invertebrates, animals)

    • Source

    • haemocytes, Armadillidium vulgare

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFQSGGGFHRGGGFHSGGSFGYR

    • Sequence Length

    • 53

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • Active against B. megaterium F04 (MBC 4.75 uM) and P. syringae DC3000 (MBC 1.18 uM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Cell membrance

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18431 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18431.

Physicochemical Information

    • Formula

    • C232H323N83O61

    • Absent Amino Acids

    • ACDEKMTVW

    • Common Amino Acids

    • G

    • Mass

    • 5250.64

    • PI

    • 12.01

    • Basic Residues

    • 11

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +11

    • Boman Index

    • -8128

    • Hydrophobicity

    • -0.73

    • Aliphatic Index

    • 14.72

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 57.31

    • Polar Residues

    • 31

DRAMP18431

DRAMP18431 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Armadillidin H, a Glycine-Rich Peptide from the Terrestrial Crustacean Armadillidium vulgare, Displays an Unexpected Wide Antimicrobial Spectrum with Membranolytic Activity

    • Reference

    • Front Microbiol. 2016 Sep 22;7:1484.

    • Author

    • Verdon J, Coutos-Thevenot P, Rodier MH, Landon C, Depayras S, Noel C, La Camera S, Moumen B, Greve P, Bouchon D, Berjeaud JM, Braquart-Varnier C