General Information

    • DRAMP ID

    • DRAMP18432

    • Peptide Name

    • Antapin (ANTP; insects, arthropods, invertebrates, animals)

    • Source

    • wild bee, Anthophora plumipes

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLLSALRKMIPHILSHIKK

    • Sequence Length

    • 19

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Active against B. subtilis, E. coli, S. aureus, and P. aeruginosa.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Helix

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18432 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18432.

Physicochemical Information

    • Formula

    • C99H171N29O20S

    • Absent Amino Acids

    • CDEFNQTVWY

    • Common Amino Acids

    • L

    • Mass

    • 2155.72

    • PI

    • 11.26

    • Basic Residues

    • 6

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +6

    • Boman Index

    • -815

    • Hydrophobicity

    • 0.295

    • Aliphatic Index

    • 134.76

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP18432

DRAMP18432 chydropathy plot

Comments Information

    • It became more helical in the presence of TFE, SDS, or anionic lipids.

Literature Information

  • ·Literature 1

    • Title

    • Structural study of a novel antimicrobial peptide isolated from the venom of bee Anthophora plumipes

    • Reference

    • J. Pept. Sci., 2014; 20:S263

    • Author

    • S. Cujov