General Information
-
DRAMP ID
- DRAMP18433
-
Peptide Name
- Cremycin-15 (nematode; invertebrates, animals)
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Source
- Caenorhabditis remanei
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Family
- Not found
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Gene
- Not found
-
Sequence
- GSEIRGPCIDRFCRVICRNNGYESGHCNRWARGCSCASWIGR
-
Sequence Length
- 42
-
UniProt Entry
- No entry found
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Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
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Target Organism
- Active against Gram-positive bacteria B. megaterium and S. marcescens (CL 14.1-17.7 uM).
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Bridge
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP18433.
Physicochemical Information
-
Formula
- C196H306N70O57S6
Absent Amino Acids
- KLMQT
Common Amino Acids
- R
Mass
- 4747.38
PI
- 8.98
Basic Residues
- 8
Acidic Residues
- 3
Hydrophobic Residues
- 10
Net Charge
- +5
-
Boman Index
- -11680
Hydrophobicity
- -0.533
Aliphatic Index
- 48.81
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 12865
Absorbance 280nm
- 313.78
Polar Residues
- 20
DRAMP18433
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Nematode-derived drosomycin-type antifungal peptides provide evidence for plant-to-ecdysozoan horizontal transfer of a disease resistance gene
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Pubmed ID
- 24434635
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Reference
- Nat Commun. 2014;5:3154.
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Author
- Zhu S, Gao B.