General Information
-
DRAMP ID
- DRAMP18437
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Peptide Name
- Oryctes rhinoceros defensin (insects, arthropods, invertebrate, animals)
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Source
- Coconut rhinoceros beetle, Oryctes rhinoceros
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Family
- Belongs to the defensin family.
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Gene
- Not found
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Sequence
- LTCDLLSFEAKGFAANHSLCAAHCLAIGRKGGACQNGVCVCRR
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Sequence Length
- 43
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UniProt Entry
- No entry found
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Protein Existence
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- Active against S. aureus.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Bridge
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- Please click DRAMP18437_predicted_structure.pdb to download.
Physicochemical Information
-
Formula
- C187H307N61O54S6
Absent Amino Acids
- MPWY
Common Amino Acids
- A
Mass
- 4466.23
PI
- 8.69
Basic Residues
- 7
Acidic Residues
- 2
Hydrophobic Residues
- 17
Net Charge
- +5
-
Boman Index
- -4029
Hydrophobicity
- 0.363
Aliphatic Index
- 84.19
Half Life
-
- Mammalian:5.5 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 375
Absorbance 280nm
- 8.93
Polar Residues
- 16
DRAMP18437
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros
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Pubmed ID
- 10561605
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Reference
- Eur J Biochem. 1999 Dec;266(2):616-23
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Author
- Ishibashi J, Saido-Sakanaka H, Yang J, Sagisaka A, Yamakawa M.