General Information

    • DRAMP ID

    • DRAMP18437

    • Peptide Name

    • Oryctes rhinoceros defensin (insects, arthropods, invertebrate, animals)

    • Source

    • Coconut rhinoceros beetle, Oryctes rhinoceros

    • Family

    • Belongs to the defensin family.

    • Gene

    • Not found

    • Sequence

    • LTCDLLSFEAKGFAANHSLCAAHCLAIGRKGGACQNGVCVCRR

    • Sequence Length

    • 43

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Active against S. aureus.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18437 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18437.

Physicochemical Information

    • Formula

    • C187H307N61O54S6

    • Absent Amino Acids

    • MPWY

    • Common Amino Acids

    • A

    • Mass

    • 4466.23

    • PI

    • 8.69

    • Basic Residues

    • 7

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 17

    • Net Charge

    • +5

    • Boman Index

    • -4029

    • Hydrophobicity

    • 0.363

    • Aliphatic Index

    • 84.19

    • Half Life

      • Mammalian:5.5 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 375

    • Absorbance 280nm

    • 8.93

    • Polar Residues

    • 16

DRAMP18437

DRAMP18437 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Purification, cDNA cloning and modification of a defensin from the coconut rhinoceros beetle, Oryctes rhinoceros

    • Reference

    • Eur J Biochem. 1999 Dec;266(2):616-23

    • Author

    • Ishibashi J, Saido-Sakanaka H, Yang J, Sagisaka A, Yamakawa M.