General Information

    • DRAMP ID

    • DRAMP18441

    • Peptide Name

    • Panusin (beta defensins; crustaceans, arthropods, invertebrates, animals)

    • Source

    • the Caribbean spiny lobster, Panulirus genus

    • Family

    • Belongs to the beta-defensin family.

    • Gene

    • Not found

    • Sequence

    • SYVGDCGSNGGSCVSSYCPYGNRLNYFCPLGRTCCRRSY

    • Sequence Length

    • 39

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal

    • Target Organism

    • Active against E. coli, K. pneumonia, S. aureus, B. subtilisspizizenii, and C. albicans.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18441 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18441.

Physicochemical Information

    • Formula

    • C178H266N54O57S6

    • Absent Amino Acids

    • AEHIKMQW

    • Common Amino Acids

    • CGS

    • Mass

    • 4266.76

    • PI

    • 8.64

    • Basic Residues

    • 4

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +3

    • Boman Index

    • -7777

    • Hydrophobicity

    • -0.405

    • Aliphatic Index

    • 34.87

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 7825

    • Absorbance 280nm

    • 205.92

    • Polar Residues

    • 27

DRAMP18441

DRAMP18441 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Panusin represents a new family of beta-defensin-like peptides in invertebrates.

    • Reference

    • Dev Comp Immunol. 2017 Feb;67:310-321

    • Author

    • Montero-Alejo V, Corzo G, Porro-Suard