General Information

    • DRAMP ID

    • DRAMP18447

    • Peptide Name

    • Gm0025x00667(75

    • Source

    • soybean, Glycine max

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RWRFLRKISSVHMFSVKALDDFRQL

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18447 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18447.

Physicochemical Information

    • Formula

    • C144H227N43O34S

    • Absent Amino Acids

    • CEGNPTY

    • Common Amino Acids

    • R

    • Mass

    • 3136.71

    • PI

    • 11.55

    • Basic Residues

    • 7

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +5

    • Boman Index

    • -6543

    • Hydrophobicity

    • -0.256

    • Aliphatic Index

    • 89.6

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 229.17

    • Polar Residues

    • 3

DRAMP18447

DRAMP18447 chydropathy plot

Comments Information

    • It inhibited the in vitro growth of X. axonopodis pv. glycines, the causative agent of the bacterial pustule disease, at 5 uM. Also active ex vivo and in vivo after vector transformation.

Literature Information

  • ·Literature 1

    • Title

    • Probing protein sequences as sources for encrypted antimicrobial peptides.

    • Reference

    • PLoS One. 2012;7(9):e45848.

    • Author

    • Brand GD, Magalh?es MT, Tinoco ML, Arag?o FJ, Nicoli J, Kelly SM, Cooper A, Bloch C Jr.