General Information

    • DRAMP ID

    • DRAMP18457

    • Peptide Name

    • Tet213 (synthetic, Trp-rich, Arg-rich)

    • Source

    • Synthetic

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • KRWWKWWRRC

    • Sequence Length

    • 10

    • UniProt Entry

    • No entry found

    • Protein Existence

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Active against S. aureus and P. aeruginosa.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18457 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18457.

Physicochemical Information

    • Formula

    • C77H105N25O10S

    • Absent Amino Acids

    • ADEFGHILMNPQSTVY

    • Common Amino Acids

    • W

    • Mass

    • 1590.92

    • PI

    • 11.72

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 4

    • Net Charge

    • +5

    • Boman Index

    • -4526

    • Hydrophobicity

    • -2.036

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 22000

    • Absorbance 280nm

    • 2200

    • Polar Residues

    • 1

DRAMP18457

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides on calcium phosphate-coated titanium for the prevention of implant-associated infections

    • Reference

    • Biomaterials. 2010 Dec;31(36):9519-26.

    • Author

    • Kazemzadeh-Narbat M, Kindrachuk J, Duan K, Jenssen H, Hancock RE, Wang R