• DRAMP ID

    • DRAMP18644
    • Peptide Name

    • KRS22
    • Source

    • Synthetic construct
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • WRWFIH
    • Sequence Length

    • 6
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Synthetic
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • [Ref.19734717] Gram-negative bacteria: Acidovorax konjaci (MEC=5 nM), Pseudomonas syringae pv. tomato DC3000 (MEC=2.5 nM), Escherichia coli DH5α (MEC=5 nM), Pectobacterium carotovorum subsp. atrosepticum (MEC=2.5 nM), Xanthomonas albilineans (MEC=2.5 nM), Xanthomonas campestris pv. vesicatoria 833 (MEC=2.5 nM), Xanthomonas campestris pv. vesicatoria 833 pilA (MEC=2.5 nM), Xanthomonas oryzae pv. oryzae 599 (MEC=0.6 nM), Xanthomonas oryzae pv. oryzae 710 (MEC=1.3 nM), Xanthomonas oryzae pv. oryzae 090 (MEC=0.3 nM);
      • Gram-positive bacterium: Clavibacter michiganensis subsp. michiganensis (MEC=1.3 nM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not foundn
    • Helical Wheel Diagram

    • DRAMP18644 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP18644.
    • Formula

    • C49H61N13O7
    • Absent Amino Acids

    • ACDEGKLMNPQSTVY
    • Common Amino Acids

    • W
    • Mass

    • 944.11
    • PI

    • 9.76
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 4
    • Net Charge

    • +2
    • Boman Index

    • -702
    • Hydrophobicity

    • -0.367
    • Aliphatic Index

    • 65
    • Half Life

      • Mammalian:2.8 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 11000
    • Absorbance 280nm

    • 2200
    • Polar Residues

    • 0

DRAMP18644

    • Function

    • High activity against XCV833 and CM at the high concentration
  • ·Literature 1
    • Title

    • Identification of novel bioactive hexapeptides against phytopathogenic bacteria through rapid screening of a synthetic combinatorial library.
    • Reference

    • J Microbiol Biotechnol. 2009 Aug;19(8):792-802.
    • Author

    • Choi J, Moon E.