• • DRAMP ID

  • DRAMP18646

• • Peptide Name

  • PAF32

• • Source

  • Synthetic construct

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • RKWHFW

• • Sequence Length

  • 6

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Synthetic

• • Biological Activity

  • Antimicrobial, Antifungal

• • Target Organism

  • • [Ref.11976121] Fungi: Penicillium digitatum PHI-26 (MIC=20 μM, IC50=7 ± 1 μM), Penicillium italicum PHI-1 (MIC=20 μM, IC50=15 ± 5 μM), Botrytis cinerea CECT2100 (MIC=40 μM, IC50=19 ± 8 μM), Fusarium oxysporum CECT2866 (MIC=80 μM, IC50=56 ± 11 μM), Saccharomyces cerevisiae W303-1A (MIC>160 μM, IC50=63 ± 10 μM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP18646.

DRAMP18646

• • Function

  • Antifungal activity against Penicillium digitatum PHI-26, Penicillium italicum PHI-1, Botrytis cinerea CECT2100, Fusarium oxysporum CECT2866, Saccharomyces cerevisiae W303-1A. All residues of PAF32 are D-animo acids.

• ·Literature 1

• • Title

  • Identification of novel hexapeptides bioactive against phytopathogenic fungi through screening of a synthetic peptide combinatorial library.

• • Pubmed ID

  • 11976121

• • Reference

  • Appl Environ Microbiol. 2002 May;68(5):2453-60.

• • Author

  • López-García B, Pérez-Payá E, Marcos JF.