General Information
-
DRAMP ID
- DRAMP18656
-
Peptide Name
- Microcin 7 (Bacteriocin; Escherichia coli, Bacteria)
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Source
- Escherichia coli
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Family
- Bacteriocin
-
Gene
- Not found
-
Sequence
- MRTGNAD
-
Sequence Length
- 7
-
UniProt Entry
- No entry found
-
Protein Existence
- Natural
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram-
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Target Organism
-
- [Ref.2861788] Gram-negative bacteria: Escherichia coli , Klebsiella pneumoniae, Salmonella typhi, Salmonella typhimurium, Salmonella sp., Shigella flexneri, Shigella sp., Proteus mirabilis
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18656.
Physicochemical Information
-
Formula
- C28H49N11O12S
Absent Amino Acids
- CEFHIKLPQSVWY
Common Amino Acids
- ADGMNRT
Mass
- 763.82
PI
- 5.59
Basic Residues
- 1
Acidic Residues
- 1
Hydrophobic Residues
- 1
Net Charge
- 0
-
Boman Index
- -2775
Hydrophobicity
- -1.271
Aliphatic Index
- 14.29
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP18656
Comments Information
Function
- Antibacterial activity against Gram-negative bacteria.
Literature Information
- ·Literature 1
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Title
- Structure and mode of action of microcin 7, an antibacterial peptide produced by Escherichia coli.
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Pubmed ID
- 2861788
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Reference
- Antimicrob Agents Chemother. 1985 May;27(5):791-7.
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Author
- Garcia-Bustos JF, Pezzi N, Mendez E.