General Information

    • DRAMP ID

    • DRAMP18657

    • Peptide Name

    • Chitinase (Bacteriocin; Streptomyces violaceusniger, Bacteria)

    • Source

    • Streptomyces violaceusniger

    • Family

    • Bacteriocin

    • Gene

    • Not found

    • Sequence

    • GDGTGPGPGP

    • Sequence Length

    • 10

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • [Ref.22915152] Inhibits mycelial growth of wood rotting fungi: Phanerochaete chrysosporium MTCC 787 (Inhibition Zone=32.60 mm), Schizophyllum commune ITCC 3751 (Inhibition Zone=27.60 mm), Gloeophyllum trabeum MTCC 355 (Inhibition Zone=30.70 mm), Polyporus agaricans ITCC 761 (Inhibition Zone=25.70 mm),Coriolus versicolor MTCC 138 (Inhibition Zone=20.60 mm), Polystictus versicolor ITCC 13 (Inhibition Zone=16.70 mm), Postia placenta MTCC 144 (Inhibition Zone=20.60 mm), Polyporus friabilis ITCC 335 (Inhibition Zone=22.60 mm).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP18657 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP18657.

Physicochemical Information

    • Formula

    • C33H50N10O14

    • Absent Amino Acids

    • ACEFHIKLMNQRSVWY

    • Common Amino Acids

    • G

    • Mass

    • 810.82

    • PI

    • 3.8

    • Basic Residues

    • 0

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 0

    • Net Charge

    • -1

    • Boman Index

    • -659

    • Hydrophobicity

    • -1.1

    • Aliphatic Index

    • 0

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 6

DRAMP18657

Comments Information

    • Function

    • Antifungal activity aginst mycelial growth of wood rotting fungi.

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of an extracellular chitinase from antagonistic Streptomyces violaceusniger.

    • Reference

    • J Basic Microbiol. 2013 May;53(5):429-39. doi: 10.1002/jobm.201100648. Epub 2012 Aug 23.

    • Author

    • Nagpure A, Gupta RK.