• • DRAMP ID

  • DRAMP18664

• • Peptide Name

  • Brevinin 15 (Brevinin-1E truncated peptide 15; Frogs, amphibians, animals)

• • Source

  • Rana esculenta

• • Family

  • Derived from the peptide Brevinin-1E

• • Gene

  • Not found

• • Sequence

  • ANFLPKIFCKITRKC

• • Sequence Length

  • 15

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anitifungal, Anti-Gram-

• • Target Organism

  • • [Ref.9748603]Gram-positive bacteria: Staphylococcus aureus ATCC 6538 (MIC=100 μg/ml), Micrococcus luteus ATCC 9341 (MIC=25 μg/ml);
    • Gram-negative bacteria: Escherichia coli ATCC 2592 (MIC=50 μg/ml), Pseudomonas aeruginosa ATCC 9027 (MIC=50 μg/ml);
    • Fungus: Candida albicans ATCC 36232 (MIC=50 μg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Alpha helix

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP18664.

DRAMP18664

• • Function

  • Antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungi.

• ·Literature 1

• • Title

  • Structure-activity analysis of brevinin 1E amide, an antimicrobial peptide from Rana esculenta.

• • Pubmed ID

  • 9748603

• • Reference

  • Biochim Biophys Acta. 1998 Sep 8;1387(1-2):239-48.

• • Author

  • Kwon MY, Hong SY, Lee KH.