General Information
-
DRAMP ID
- DRAMP18670
-
Peptide Name
- AI-hemocidins 4 (Hb-1 truncated peptide)
-
Source
- Arca inflata
-
Family
- Belongs to truncated Hb-1
-
Gene
- Not found
-
Sequence
- VLASKNFGDK
-
Sequence Length
- 10
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+
-
Target Organism
-
- [Ref.28661457] Gram-positive bacterium: Bacillus subtilis ATCC 6633 (MIC=69.55 μM).
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18670.
Physicochemical Information
-
Formula
- C48H79N13O15
Absent Amino Acids
- CEHIMPQRTWY
Common Amino Acids
- K
Mass
- 1078.23
PI
- 8.56
Basic Residues
- 2
Acidic Residues
- 1
Hydrophobic Residues
- 4
Net Charge
- +1
-
Boman Index
- -1517
Hydrophobicity
- -0.34
Aliphatic Index
- 78
Half Life
-
- Mammalian:100 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP18670
Comments Information
Function
- Antibacterial activity against the Gram-positive bacteria.
Literature Information
- ·Literature 1
-
Title
- Antibacterial Activity of AI-Hemocidin 2, a Novel N-Terminal Peptide of Hemoglobin Purified from Arca inflata
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Pubmed ID
- 28661457
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Reference
- Mar Drugs. 2017 Jun 29;15(7). pii: E205.
-
Author
- Li C, Zhu J, Wang Y, Chen Y, Song L, Zheng W, Li J, Yu R.