General Information
-
DRAMP ID
- DRAMP18675
-
Peptide Name
- Peptide 4 (Mollusca/molluscs/mollusks, invertebrates, animals)
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Source
- Marine snail Rapana venosa
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- SLPPTLEEEFNMKKMG
-
Sequence Length
- 16
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
-
Target Organism
-
- [Ref.21703315] Gram-positive bacterium: Staphylococcus aureus;
- Gram-negative bacterium: Klebsiella pneumoniae
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP18675.
Physicochemical Information
-
Formula
- C81H131N19O26S2
Absent Amino Acids
- ACDHIQRVWY
Common Amino Acids
- E
Mass
- 1851.16
PI
- 4.78
Basic Residues
- 2
Acidic Residues
- 3
Hydrophobic Residues
- 3
Net Charge
- -1
-
Boman Index
- -2568
Hydrophobicity
- -0.794
Aliphatic Index
- 48.75
Half Life
-
- Mammalian:1.9 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 4
DRAMP18675
Comments Information
Function
- Antibacterial activity against Gram-positive and Gram-negative bacterium.
Literature Information
- ·Literature 1
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Title
- Antimicrobial proline-rich peptides from the hemolymph of marine snail Rapana venosa.
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Pubmed ID
- 21703315
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Reference
- Peptides. 2011 Jul;32(7):1477-83.
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Author
- Dolashka P, Moshtanska V, Borisova V, Dolashki A, Stevanovic S, Dimanov T, Voelter W.